李亚东等发现下丘脑促进天鹅神经发生可调控学习记忆和焦虑

含义在于，提出了通过减低超凡高度，有助于海燕大脑牵涉到，提升认知战斗能力的新的策略性。通过丰富环境、国家主义等减低超凡的方具体法则均有可能达致减低认知的目的。正因如此的是，该策略性可以可用拔预乌拉克尔海默病早期由大脑丢失惹来的的认知障碍。

郭亚东和罗艳佳博士为专著联合第一作者，宋娟为唯一的通讯作者。该研究课题获得复旦大学黄志力课题四组在躯Spike就有许多公司。

郭亚东博士关注超凡系统以及超凡诱导求学遗忘和特质的大脑交叉点研究课题，运用于在躯电生物体就有、高分辨率单/双光子成像、在躯多通道钙信号就有、生物学和光/工程学基因突变学操控方具体法则等电子技术，阐释了腹侧角化大脑节交叉点诱导想法相关超凡的最主要缺少适度(5, 6)（Molecular Psychiatry，2021；Nature Communications，2018）；注意到下丘脑超凡交叉点有助于海燕大脑牵涉到、提升遗忘分离出战斗能力的缺少适度和独特系统，提出了通过减低超凡高度，有助于海燕大脑牵涉到提升求学遗忘的新的思路（eLife，2020；Nature Neuroscience，2022）。

此前期引述：Mol Psychiatry：复旦黄志力四组注意到腹侧苍白球诱导想法不道德和超凡

美国政府杰克逊维尔大学惠顿分校宋娟课题四组诚聘博士后，详细信息请参考：

宋娟课题四组近几年的代表作：

1. Asrican B#, Wooten J#, Li Y, Quintanilla L, Zhang F, Bao H, Yeh CY, Wander C, Luo YJ, Olsen RHJ, Lim SA, Jin P, Song J* (2020). Neuropeptides modulate local astrocytes to regulate adult hippocampal neural stem cells. Neuron 108(2):349-366.

2. Li Y, Bao H, Luo Y, Yoan C, Sullivan HA, Quintanilla L, Wickersham IR, Lazarus M, Shin YY, Song J* (2020). Supramammillary nucleus synchronizes with dentate gyrus to regulate spatial memory retrieval through glutamate release. eLife doi: 10.7554/eLife.53129.

3. Yeh CY#, Asrican B#, Moss J, Quintanilla L, He T, Mao X, Cassé F, Gebara E, Bao H, Lu W, Toni N, Song J* (2018). Mossy cells control adult neural stem cell quiescence and maintenance through a dynamic balance between direct and indirect pathways. Neuron 99(3):493-510 (Featured article, issue highlights).

4. Bao H#, Asrican B#, Li W#, Gu B, Wen ZX, Lim ZA, Haniff I, Ramakrishnan C, Deisseroth K, Philpot B, Song J* (2017). Long-range GABAergic inputs regulate neurl stem cell quiescence and control adult hippocampal neurogenesis. Cell Stem Cell 21(5):604-617 (Cover article, featured article, issue highlights, recommended by F1000, selected as Best Articles in 2017 in Cell Stem Cell).

参考文献（上下转动察看）：

1. J. S. Farrell, M. Lovett-Barron, P. M. Klein, F. T. Sparks, T. Gschwind, A. L. Ortiz, B. Ahanonu, S. Bradbury, S. Terada, M. Oijala, E. Hwaun, B. Dudok, G. Szabo, M. J. Schnitzer, K. Deisseroth, A. Losonczy, I. Soltesz, Supramammillary regulation of locomotion and hippocampal activity. Science 374, 1492-1496 (2021); published online EpubDec 17 (10.1126/science.abh4272).

2. S. Chen, L. He, A. J. Y. Huang, R. Boehringer, V. Robert, M. E. Wintzer, D. Polygalov, A. Z. Weitemier, Y. Tao, M. Gu, S. J. Middleton, K. Namiki, H. Hama, L. Therreau, V. Chevaleyre, H. Hioki, A. Miyawaki, R. A. Piskorowski, T. J. McHugh, A hypothalamic novelty signal modulates hippocampal memory. Nature 586, 270-274 (2020); published online EpubOct (10.1038/s41586-020-2771-1).

3. N. P. Pedersen, L. Ferrari, A. Venner, J. L. Wang, S. B. G. Abbott, N. Vujovic, E. Arrigoni, C. B. Saper, P. M. Fuller, Supramammillary glutamate neurons are a key node of the arousal system. Nature communications 8, 1405 (2017); published online EpubNov 10 (10.1038/s41467-017-01004-6).

4. Y. Li, H. Bao, Y. Luo, C. Yoan, H. A. Sullivan, L. Quintanilla, I. Wickersham, M. Lazarus, Y. I. Shin, J. Song, Supramammillary nucleus synchronizes with dentate gyrus to regulate spatial memory retrieval through glutamate release. Elife 9, (2020); published online EpubFeb 26 (10.7554/eLife.53129).

5. Y. D. Li, Y. J. Luo, W. Xu, J. Ge, Y. Cherasse, Y. Q. Wang, M. Lazarus, W. M. Qu, Z. L. Huang, Ventral pallidal GABAergic neurons control wakefulness associated with motivation through the ventral tegmental pathway. Molecular psychiatry, (2020); published online EpubOct 14 (10.1038/s41380-020-00906-0).

6. Y. J. Luo, Y. D. Li, L. Wang, S. R. Yang, X. S. Yuan, J. Wang, Y. Cherasse, M. Lazarus, J. F. Chen, W. M. Qu, Z. L. Huang, Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D1 receptors. Nature communications 9, 1576 (2018); published online EpubApr 20 (10.1038/s41467-018-03889-3).

7. Y. D. Li, Y. J. Luo, Z.K. Chen, L. Quintanilla, Y. Cherasse , L. Zhang, MLazarus, Z.L. Huang, J. Song, Hypothalamic modulation of adult hippocampal neurogenesis in mice confers activity-dependent regulation of memory and anxiety-like behavior. Nature Neuroscience, (2022) ; published online Epub May 6, (10.1038/s41593-022-01065-x).

本文版权归创作者所有。

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